Best Rat Poison Reviews – Comparison 2021

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Rats invade our houses looking for shelter and food. They interact socially with humans and are found in almost all human habitats. Rats and mice are known to be fond of causing significant damages where they inhabit, that is in homes, farms, and business premises. Finding the best rat poison is important to completely get rid of rats. Here comes our complete guide on how to get rid of mice indoors and outdoors. The best mouse poison should completely wipe out these home invaders. We have distinguished facts from myths to help you solve the mice infestation from the root.

Best Rat Poison Reviews

  • 4.5 Customer Rating
  • Formulation: Poison Bar
  • Type: Fast Acting
  • Best Use: Indoor/Outdoor
  • Ingredients: Bromadiolone
  • Size: 1 Large Bar
  • Price: $$

  • 4.1 Customer Rating
  • Formulation: Poison Chunks
  • Type: Fast Acting
  • Best Use: Indoor/Outdoor
  • Ingredients: Bromethalin
  • Size: 64 Chunks
  • Price: $

  • 4.1 Customer Rating
  • Formulation: Poison Blocks
  • Type: Slow Acting
  • Best Use: Indoor/Outdoor
  • Ingredients: Diphacinone
  • Size: 144 Blocks
  • Price: $$

  • 4.1 Customer Rating
  • Formulation: Poison Pellets
  • Type: Fast Acting
  • Best Use: Indoor/Outdoor
  • Ingredients: Brodifacoum
  • Size: 4 Small Trays
  • Price: $$$

1. Just One Bite II Bar – Best Rat Poison

Best Rat Poison Just One Bite II Bar

Farnam Just One Bite II bar is a single feed rat poison. It has an active ingredient called Bromadiolone which kills both mice and rats altogether in a single feed and it will also work against Warfarin-resistant rats.

It contains special nibble ridges that rodents love chewing. Made with grains and seeds that are favorable to rats and mice. You can also break the poison bar into smaller pieces for specific cases such as baiting and wall mounting.

Since rats are very picky and they don’t really like to eat food infested with insects, this rat poison is treated with S-methoprene to protect it from insects infestation. For total eradication of these pesky rodents, Just One Bite is capable of smashing various types of rats such as Norway rats, roof rats, and house mice.


  • The bait bars are breakable into smaller pieces allowing you to target different rodent sizes even in narrow spaces.
  • Just one bite kills within 2 to 5 days of a single feed.
  • This rat bait contains grains and seeds that are favorable to all kinds of rodents which guarantees that they will not miss it without taking a bite.
  • The fact that it is a slow killer gives time for the rat infestation to feed, ultimately, eradicating the entire rat colony.


  • Highly poisonous, requires you to be extra careful when handling it by taking all precautions and wearing gloves while placing them.
  • Not safe for children or pets. Should be placed inside a rat bait station.

2. Tomcat Bait Chunx Pail – Best Mouse Poison

Best Mouse Poison Tomcat Bait Chunx Pail

Motomco Tomcat mouse and rat Bromethalin bait chunx, with an active ingredient Bromethalin which has a toxic power to reach out stubborn roof rats, Norway rats, and house mice.

These rodenticide bait chunks have the capability of taking down the famous anticoagulant resisting mice and rats, meaning it will also be effective against poison-resistant rats. It has the ability to kill these pesky rodents with less bait.

The bucket contains roughly 64 chucks that you can place in reusable rat bait stations for long-term control of rat population. You can place them both indoors and outdoors. Most importantly, placing it at home and in the surrounding of agricultural buildings. It will allow you to start seeing results within one or two days.


  • A fast-acting rat and mouse poison kills within 1 or 2 days.
  • High toxic ingredients, capable of killing many rats with less bait.
  • Effective in controlling severe rodent infestations. Each block is enough to kill up 12 rats.
  • Formulated with maximum palatability and weatherability that you can use during all seasons.


  • Not safe, very toxic, so make sure to keep out of reach of children and pets. Each chunk has a hole in it so you can place them inside plastic bait stations for safety.
  • Some rodents seem to avoid it. We recommend trading off baits from time to time with traditional Diphacinone poisons.

3. JT Eaton Bait Block Rodenticide – Best Rat Killer

Best Poison for Killing Rats JT Eaton Bait Block Rodenticide

The JT Eaton 709- PN bait killer is a 1st generation anticoagulant killer bait. Formulated with Diphacinone as the active ingredient and have a peanut butter like flavor to effectively attract and eradicate rats and mice.

The enticing aroma of peanut butter will surely captivate the rodents attention. It is a slow killer, it will allow them to feed on it for a few days. Ultimately, it will exterminate the rat or mouse infestation in your home or business premises.

The bucket contains 144 rodenticide blocks in a resealable pail. Ideal for long-term use for garages, attics, or basements to keep rats and mice away. Just determine where you see these rodents, place the blocks in mouse bait stations to ensure it’s out of reach of children or pets, and it will dramatically reduce the rodent problem.


  • A large pack, ideal for long-term use with a tight resealable pail.
  • Diphacinone works perfectly on rats and mice.
  • The fact that it contains peanut butter aroma ensures that rodents will not be able to resist the luring bait.
  • Comes with one-year limited warranty.


  • It takes a bit long to start seeing results. This is due to being a slow killer which means the rodents has to eat some every day for 4-7 days in a row to die.
  • Some packages of this product come with a tiny hole in the blocks that doesn’t fit all bait stations.

4. D-Con Ready Mix Bait Pellets – Best Mouse Killer

Best Posion for Killing Mice D-Con Ready Mix Bait Pellets

D-Con rat and mouse bait bits trays contain Brodifacoum as an active ingredient. Capable of killing rats and mice with a single feed. It is also capable of killing Warfarin resistant mice and rats with one lethal dose.

These highly concentrated D-Con bait trays will allow you to see results within 4 or 5 days against large infestation of rats and mice. The bits have a high level of toxicity that will knock out rodents easily.

Each package contains 4 small bait trays that you can easily place in hidden corners where rodents activity is evident. However, the bits can be easily scattered out of the tray. To avoid this, do not remove the entire paper cover, instead only cut about half an inch in the center of the paper cover. This will provide access for rodents without scattering the bits outside the tray.


  • Pre-filled ready to use trays makes it easy to place and set up.
  • Contains larger pellets, guarantees killing rats, mice, and other small rodents effectively.
  • Allows you to see fast results even against poison resistant mice and rats.
  • Less poison will be used to kill as it is effective with just one feed and the rat or mouse will die within 4 or 5 days of feeding.


  • Not safe for humans and animals, fatal if swallowed.
  • It is very expensive compared to other products.

Best Rat Poison Comparison

Just One Bite II Bar
Bar8 poundsNoRats + Mice
Tomcat Bait Chunx PailChunks4 poundsNoRats + Mice
JT Eaton Bait Block Rodenticide
Blocks9 poundsNoRats + Mice
D-Con Ready Mix Bait PelletsPellets4 x 3 ouncesNoRats + Mice

How to Get Rid of Rats? Find the Best Rat Poison

Making the right selection for the tools you need at work is very essential for perfect results. Product selection is very sensitive in this context. This is because when you chose a product, you definitely expect it to deliver good results. Dr. Jonathan Wade, explains that a perfect understanding of active substances in rat poisons is a key point in achieving a perfect rodent control. Here we feature key points to emphasize on when going to look for the best rat poison in the market. While keeping in mind to always be careful when handling and placing these products, as some of them are highly toxic.

  • Active Ingredients

The active ingredient in rat poison is normally indicated on the product packaging sticker. Often, manufacturers get a bit confusing in bringing out this message. In this confusion, you should not be actually misled in the whole marketing mix. Taking into consideration some essential facts and figures while looking for the best active ingredient would help you arrive at informed decisions on the best mice poison for your preferred purpose.

Having in mind how much the infesting rats eat, the power of the active ingredient and most importantly, the contrast between the toxicity defines what ingredient you should opt for. Examples of the active ingredients in rat poisons include Bromethalin, Alphachloralose, Bromadiolone, Brodifacoum, and Difenacoum among many others.

  • Slow Acting & Fast Acting Poisons

Rat and mouse poisons can be divided into two categories slow-acting poison baits and fast-acting poison baits. Slow acting poisons are usually called first-generation anticoagulant. However, fast-acting poisons have two types second-generation anticoagulant and non-anticoagulants.

  1. Slow acting first-generation anticoagulant: This type requires multiple exposures to the poison to deliver a lethal dose. It kills rats after consuming it for several days and up to a week. Since it requires multiple feeding, it is safer for everyone if consumed by mistake including humans, pets, and non-targeted animals.  However, some species of rats and mice developed a resistant towards these types of poisons and they may still survive. Active ingredients of this type include Warfarin. There is an antidote for this type of poison which is vitamin K.
  2. Fast acting second-generation anticoagulant: This type kills within a single feed of exposure to the poison. They will eventually die after four or five days of consumption. Active ingredients include Bromadiolone and Brodifacoum. This type is definitely dangerous for humans and pets. It should be used with extreme caution. The antidote is also vitamin K.
  3. Fast acting non-anticoagulants: It kills within a single feed. Rats and mice die within one or two days of consumption. Active ingredients of this type of poison include Bromethalin. There is no antidote for this type. This type is the most dangerous and the fact that there is no antidote for it makes it lethal for everyone.
  • Child & Pet Friendliness

Unfortunately, our children and pets may end up consuming the rat poison. They may be affected or not. This all depends on the type of rat poison used. Some rat poisons are green or blue in color mainly for pets not to notice them, whereas others have anticoagulant as an active ingredient thus have minimal harm to children and pets.

However, experts advise to always purchase the antidote, read all the warnings carefully, and use with caution. Also, rat and mouse poison should be only used inside bait containers. These bait stations or containers are tightly sealed, they open with a special key lock that comes with the box container. These bait containers have a small hole opening for rats and mice to enter and feed while avoiding children and pets from reaching the contained poison.

  • Knowing the Difference Between Mouse & Rat

Interestingly, the smell of rats is quite uncomfortable for mice. The smell affects behavior and recreation of mice. Visually both rats and mice are one and the same thing to us. In a real sense, they are very different. Rats are actually a medium size whereas mice are comparatively tiny and sparrow in size. The major similarity between the two is that they are rodents and have long thin tails. Getting things right here enables you to pick not only the correct size but also the appropriate toxicity level.

Make the right choice in terms of the size of the poison. Choosing very big sizes of baits would make the small mice avoid the poison if they were to eat it. At the same time, too small sizes might as well underdose the rats and make them avoid it completely.

  • Choosing the Correct Bait Station

Bait stations are devices that are intended to protect children, cats, and dogs from accidental poisoning. It holds the poison block or chunks securely inside. Preventing children or pets from coming into contact with the rodenticide or poison. Rats and mice just don’t die inside these bait station, so don’t expect to find them dead inside. Instead, they enter the station containers, eat the bait, and then leave. You will usually find the rodent dead somewhere else. Finding even a little bit of bait missing means it is working.

Bait stations come in disposable and reusable options. It all depends on the size of the rodent infestation available. If you only noticed a couple of rodents in your garage or basement then disposable bait stations is an easier choice. They allow you to use each station then directly dispose of it once the problem is solved. If you have a large rodent problem that persist throughout the year then reusable bait stations would be the best choice.

  • Choosing the Correct Place for the Bait Killer

As rats can be found both in the house and outside the house, it is essential to understand what type of killer to use indoors and outdoors. Rats are not fond of appearing in open areas. Place the poison baits strategically parallel to the wall or in some corner making sure it is parallel to the direction of the rats along the wall. The entryway to the station should always be facing out from the object it is set against. For mice, place the bait stations 8 to 12 feet apart. For rats, place the bait stations 15 to 30 feet apart.

Rat baits are highly recommended to be used indoors. This is because placing the baits is easily hidden in hot spots to kill as many rats as possible. Placing the bait in a well-lighted place would make no sense if you are aiming at getting rid of rats. Places like the kitchen are appropriately suited for non-poisonous rat control, for health safety purposes. As a result, underneath furniture are ideal places to have some of the bait. As well as, they can be used outdoors and indoors such as in the attic, garage, basement, and along the home perimeter. While these bait stations are child and pet resistant, however, you should not place them in areas where children and pets regularly frequent.

The Best Mouse Poison Type

There are two types of rat poisons. You would realize this when you have to choose between a single or multi-feed.

  • Multi-Feed

Multi-feed baits are poisons that are lesser toxic and ought to be administered to the rats gradually. The rats then gradually die after five to seven days of consumption. Well when using this method, you should be very patient.

Multi feeding is disadvantaged in some ways. Rats can be canning as they develop sensitivity. Normally, a rat would have a sample of any new eatery by having small bites. These small bites are normally not enough to have the rats well dosed. Funnily, if the rat gets sick, it will stay away from that poison with its pack. What next? The bait will be probably a waste.

Rats do not vomit. They have a protective means of saving themselves from poisonous items. When they have nausea, their remedy is to go for clay. They feed on clay which acts as a detoxifier. Clay dilutes the poison and as a result, makes it useless. As a result, even the best mouse bait is not recommended in this case.

  • Single-Feed

Single feeding baits are meant to kill once and for all. That explains why single feeding entails stronger and very toxic. This type of rat poison is normally faster when you compare it to the multi-feeding methods. You would rarely find the single feed poisons in local stores. The toxicity of the poison makes it dangerous to sell them so readily. They can only be bought online.

However, single feed poisons are very dangerous. It is advisable to use them with antidotes as a safety measure, in case it is not consumed by the targeted victim. You can also take your pets and children on a temporary vacation so you can ensure they do not consume the poison until the problem is taken care of.

Check some of our best pest control guides.

Finding the Best Mouse Killer Method

Here we discuss the main difference between the two most famous ways of getting rid of rats.

  • Rat Trap

They are mainly designed to catch rats rather than killing them. A non-poison food bait is placed in the cage. The food bait attracts the rat. When the rat has made its way into the trap, a designed mechanism suddenly shuts the door and traps it at the entrance of the trap. At this point, the fate of the animal is in the trap setter’s custody. He or She may decide to carry it alive and throw it far from the prohibited area. Rather, it may be killed without mercy!

There are different types of traps. The first the glue-based trap. Normally, it does not contain any poison. Glue is evenly spread on it and it is then placed as a trap. The best place to have them is where rats are frequent. The rats would die of hunger and dehydration in the trap. There is the wired trap. These traps are fixed with funnel-shaped wires in them. The funnel-shaped wire is fitted into the cage with the larger opening facing the entrance. The traps are made using the amazing rat adaptation of flexibility. You can check our article of the best mouse traps to know more about different types of traps.

  • Rat Poison

Also referred to as rodenticides, they are lethal substances that are meant for the rats and mice problems. However, poison is never better than other pest control methods as it can put your loved ones at risk from contamination. If you are aware of the risk, then rat poison can be a good solution when other solutions have failed to terminate the rat infestation in your home, corps, vegetation, or business premises. Once the rat consumes the poison, it may die immediately or die after few days. If you keep wondering what kills the rats in these rodenticides, we shall answer your unanswered questions.

The poisons have active ingredients that act as the main killers. The rodenticides have varying volumes of active ingredients, with varying toxicity in them. In terms of rodenticides, the best rat killer solely depends on various factors like toxicity, actives and how much the rat eats. Well, rat poisons rarely need close monitoring as opposed to rat traps which might need very close monitoring.

How to Use Rat or Mouse Poisons

  1. Prevention is always better than cure. It’s advisable to take the garbage away while always keeping it tightly closed. Use tightly sealed containers for food. Don’t leave food or even pet food open overnight. Seal up holes and cracks in the house. Look for repelling methods to use.
  2. Rodents are smart and they can learn to identify toxic baits. This is known as bait shyness. To stop this from happening, it’s always advised to use pre-baiting methods. This works by placing non-toxic baits in the corners you are intending to use the toxic bait. This will accustom the rodents to the baits areas and will condition them to come for more.
  3. Always use bait stations that allow access to rodents only. Stations that are tightly locked and will leave no space for children or pets to mess with.
  4. Use different sizes of bait stations for rats and mice. Rats are bigger in size than mice, therefore, require bigger bait stations.
  5. Place poison baits stations wherever you see rodent activity. The number of bait stations must directly correspond to the degree of the rat infestation available.
  6. Change poison baits frequently. Using different poisons with different active ingredients will ensure complete extermination of the infestation.
  7. Wear disposable gloves when baiting to prevent your odor from lingering on the bait stations. Human odors might lead to rodents avoiding the bait altogether.
  8. Choose ready to use products that don’t require mixing.
  9. Go for low-risk rodenticides over high-risk ones. Choose EPA approved products.
  10. Always follow the labeled instructions of use and disposal provided by the manufacturer.
  11. Store bait poisons in their original container to avoid any accidents.
  12. If accidental exposure or consumption occurs, call 911 or Poison Control immediately.

Bottom Line

As a matter of fact, rats and mice can be stopped from entering your place once and for all. It solely goes back to you as an individual. It is very key that you understand the various considerations to look at before you make a decision, and knowing the thin line between the best rat killer and the best rat poison. By knowing these considerations, you will end up with the best mouse poison to completely get rid of mice in your house once and for all. Lastly, we hope we could inform you on various ways to solve the rats or mice problem from the roots and helped you in choosing the best mouse killer.

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